Anti-CASP3 Polyclonal Antibody
應用 WB IHC
稀釋比例WB 1:500-2000. IHC 1:80.
交叉反應Human Mouse

產(chǎn)品型號：K101291P

更新時間：2022-08-15

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Anti-CASP3 Polyclonal Antibody

英文名稱	Anti-CASP3 Polyclonal Antibody
宿主	Rabbit
別名	CPP32;CPP32B;SCA-1;SREBP cleavage activity 1;Cysteine protease CPP32
應用	WB IHC
稀釋比例	WB 1:500-2000. IHC 1:80.
交叉反應	Human Mouse
蛋白分子量	31kDa
Gene ID	836
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human CASP3
性狀	液體
Public Immunogen Range	A synthetic peptide of human CASP3
Subcellular Locations	Cytoplasm
Swiss Prot	P42574
克隆類型	Polyclonal Antibody
背景資料	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.