Anti-IL12 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106473P

更新時(shí)間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

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Anti-IL12 Polyclonal Antibody

英文名稱	Anti-IL12 Polyclonal Antibody
宿主	Rabbit
別名	IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A
應(yīng)用	WB
稀釋比例	WB 1:3000.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	52kDa
Gene ID	3592
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human IL12
性狀	液體
Public Immunogen Range	A synthetic peptide of human IL12
Subcellular Locations	Cell membrane Secreted
Swiss Prot	P29459
克隆類型	Polyclonal Antibody
背景資料	IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.