Anti-Desmin Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106550P

更新時間：2022-08-15

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Anti-Desmin Polyclonal Antibody

英文名稱	Anti-Desmin Polyclonal Antibody
宿主	Rabbit
別名	CSM1;CSM2;LGMD2R;DES;Desmin
應(yīng)用	WB
稀釋比例	WB 1:3000.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	65kDa
Gene ID	1674
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human Desmin
性狀	液體
Public Immunogen Range	A synthetic peptide of human Desmin
Subcellular Locations	Cell membrane Cytoplasm sarcolemma
Swiss Prot	P17661
克隆類型	Polyclonal Antibody
背景資料	Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells. A desmin related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I). CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function.