Recombinant Human IL-12 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence （Arg23-Ser219&Ile23-Ser328） of Human IL-12 .

產(chǎn)品型號(hào)：P00024

更新時(shí)間：2025-08-29

廠商性質(zhì)：生產(chǎn)廠家

訪問量：1673

服務(wù)熱線

010-50973130

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

細(xì)胞相關(guān)產(chǎn)品

細(xì)胞因子細(xì)胞培養(yǎng)耗材鱟試劑平衡鹽溶液細(xì)胞檢測(cè)試劑添加劑輔助試劑細(xì)胞分離液細(xì)胞凋亡檢測(cè)試劑盒動(dòng)物血清細(xì)胞培養(yǎng)試劑

查看全部產(chǎn)品

相關(guān)文章

白細(xì)胞介素2（IL-2）信號(hào)通路

白細(xì)胞介素之促炎細(xì)胞因子

細(xì)胞因子風(fēng)暴|敵我不分的細(xì)胞因子

一文了解細(xì)胞因子

WB實(shí)驗(yàn)如何幫助我們理解神經(jīng)退行性疾病發(fā)生機(jī)制？

產(chǎn)品介紹

Known as	Interleukin-12 subunit alpha,IL-12A,Cytotoxic lymphocyte maturation factor 35 kDa subunit,CLMF p35,IL-12 subunit p35,NK cell,IL12A
Derived from	HEK293
Purity	Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.Less than 0.1 ng/?g (1 IEU/?g).
Formulation	Lyophilized from a 0.2 μM filtered solution of PBS,pH7.4
Shipping	The product is shipped at ambient temperature.Upon receipt, store it immediay at the temperature listed below.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 8 months
Reconstitution	Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 6X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.
Amino Acid Sequence	RNLPVATPDPGMFPCLHHSQNLLRAVSNMLQKARQTLEFYPCTSEEIDHEDITKDKTSTVEACLPLELTKNESCLNSRETSFITNG SCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEEPDFYKT KIKLCILLHAFRIRAVTIDRVMSYLNAS&IWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQ VKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSS DPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNS RQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWASVPCS
Background	IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN- γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN- γ . T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.

Recombinant Human IL-12 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg23-Ser219&Ile23-Ser328) of Human IL-12 .

上一個(gè)：P00025Recombinant Human IL-15